RESEARCH

PUBLICATIONS

model capsid

Exploring the Design Rules for Efficient Membrane-Reshaping Nanostructures

Phys. Rev. Lett. 125.228101 (2020); First Author

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Developed a genetic algorithm, coupled with a molecular dynamics model for desiging nanoparticles optimised for cell entry. Identified rules which govern successful membrane crossing, and the dynamics associated with them.

model summary

Phase separation in the outer membrane of Escherichia coli

PNAS 118.44 (2021); Contributing Author

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Contributed by developing a machine learning model for automatically labelling pore in AFM images of E-coli.

UNPUBLISHED/IN REVIEW

collagen fibril identification

Guiding self assembly of coarse grained collagen mimetic molecules

Expanded upon work by Hafner et. al. by developing a new system for characterising collagen mimetic fibrils in simulation, and using evolutionary algorithms to drive their assembly.

This work made up the second half of my thesis and is currently being expanded upon for a future publication.

OTHER WORK

NET

Human Immunomodulation in Space

Development of novel experiments for investigation into immune recovery in space.

Modelling of transmission of sunlight in extraterrestrial environments.

How can we maintain healthy immune response in future Martian settlements?

NET

Are Rainforests Random?

Network analysis of the BCI rainforest plot to detect communities.

Analysis of the traits of subcommunities.

Are traits randomly distributed or is there some pattern?

GODS

Using GAs to Design Nanoparticles

Developed a genetic algorithm to maximise cell membrane deformation by nanoparticles in simulations.

Are there fundamental similarities between good designs? Do recognisable functional features appear?